PharmacyCodes



Fludrocortisonum [Inn-Latin] en es it fr

Fludrocortisonum [Inn-Latin] Brand names, Fludrocortisonum [Inn-Latin] Analogs

Fludrocortisonum [Inn-Latin] Brand Names Mixture

  • No information avaliable

Fludrocortisonum [Inn-Latin] Chemical_Formula

C21H29FO5

Fludrocortisonum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic/fludro.htm

Fludrocortisonum [Inn-Latin] fda sheet

Fludrocortisonum [Inn-Latin] msds (material safety sheet)

Fludrocortisonum_[Inn-Latin] MSDS

Fludrocortisonum [Inn-Latin] Synthesis Reference

No information avaliable

Fludrocortisonum [Inn-Latin] Molecular Weight

380.45 g/mol

Fludrocortisonum [Inn-Latin] Melting Point

No information avaliable

Fludrocortisonum [Inn-Latin] H2O Solubility

140 mg/L

Fludrocortisonum [Inn-Latin] State

Solid

Fludrocortisonum [Inn-Latin] LogP

1.49

Fludrocortisonum [Inn-Latin] Dosage Forms

Tablet

Fludrocortisonum [Inn-Latin] Indication

For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.

Fludrocortisonum [Inn-Latin] Pharmacology

Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.

Fludrocortisonum [Inn-Latin] Absorption

No information avaliable

Fludrocortisonum [Inn-Latin] side effects and Toxicity

Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.

Fludrocortisonum [Inn-Latin] Patient Information

Fludrocortisonum [Inn-Latin] Organisms Affected

Humans and other mammals